VIROLOGY: Shifting Landscapes

Landscapes, space and equilibrium: shifting viewpoints

The classical view of ecological systems has been one that assumes a state of equilibrium and stability; this is encapsulated in the ‘balance of nature’ paradigm. Over the last 30 years ecologists and biogeographers have rejected the view that ecological systems are inherently stable or at some sort of equilibrium. Instead a nonequilibrium view, emphasizing the role of chance events such as dis...

Deep Learning Design for Sustainable Innovation within Shifting Learning Landscapes

Changes in the underpinning technologies for TEL is occurring at a pace that we have never before experienced, and this is unlikely to slow down. This necessitates a broader and more profound understanding of design that needs to be more future-proof than relying on the latest or emerging technologies and yet embraces the collaborative, multimodal and ubiquitous nature of learning in 21C. In ad...

Shifting fitness landscapes in response to altered environments.

The role of adaptation in molecular evolution has been contentious for decades. Here, we shed light on the adaptive potential in Saccharomyces cerevisiae by presenting systematic fitness measurements for all possible point mutations in a region of Hsp90 under four environmental conditions. Under elevated salinity, we observe numerous beneficial mutations with growth advantages up to 7% relative...

Virology

This volume of the Handbook of Behavioral Neurobiology contains a wealth of information on the neural control of movement. Overall, the approach of the authors is to stress basic experimental data. Therefore, the book will be an excellent reference source for basic scientists as well as clinicians. The first chapters of the book examine the role of muscle in movement. These chapters discuss rec...

Virology.